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Patty Kiesler (Fed)
Biologist
Patty is a Biologist in the NIST Genome Editing Program. Her work focuses on developing control materials and genome editing control assays that can be used in the advancement of animal biotechnology products created using genome editing technologies (please visit the project page for more information). She also contributes to the efforts of the NIST Genome Editing Consortium to implement measurement assurance for assays that evaluate genome editing outcomes.
Research interests
- Genome editing measurement assurance
- Genome editing control materials and datasets
- CRISPR/Cas genome editing systems
- End-to-end genome editing workflows
- Editing reagent qualification
- Characterization of genome editing outcomes via Next Generation Sequencing (NGS) based technologies
PAST PUBLICATIONS
Bai R, Balog A, Kiesler P, Arjona D, Cui H. Comment on the Criteria for Interpretation of Mitochondrial tRNA Variants. Genetics in Medicine, 2020, 22 (18): 1418-1419
Jones K, Bryant S. Luo J, Kiesler P, Koontz S, Warrn J, Malech H, Kang E, and Dveksler G. Recombinant Pregnancy-Specific Glycoprotein 1 Has a Protective Role in a Murine Model of Acute Graft-versus-Host Disease. Biology of Blood and Marrow Transplantation, 2019, 25 (2): 193-203
Kiesler P, Fuss IJ, and Strober W. Experimental Models of Inflammatory Bowel Disease. CMGH Cellular and Molecular Gastroenterology and Hepatology, 2015, 1 (2): 154-170
Park Y, Choi S, Kiesler P, Gil-Krzewska A, Borrego F, Weck J, Krzewski K, and Coligan JE. Complex Regulation of Human NKG2D-DAP10 Cell Surface Expression: Opposing Roles of the γc cytokines and TGF-β1. Blood, 2011, 118 (11): 3019-3027
Kiesler P, Haynes PA, Shi L, Kao PN, Wysocki VH, and Vercelli D. NF90 and NF45 Regulate HS4-Dependent Interleukin-13 (IL13) Transcription in T Cells. The Journal of Biological Chemistry, 2010, 285 (11): 8256-8267
Kiesler P, Shakya A, Tantin D, and Vercelli D. An Allergy-Associated Polymorphism in a Novel Regulatory Element Enhances IL13 Expression. Human Molecular Genetics, 2009, 18 (23): 4513-4520
Cameron L, Webster RB, Strempel JM, Kiesler P, Kabesch M, Ramachandran H, Yu L, Stern DA, Graves PE, Lohman IC, Wright AL, Halonen M, KlimeckiWT, and Vercelli D. Th2 Cell-Selective Enhancement of Human IL13 Transcription by IL-13-1112C>T, a Polymorphism Associated with Allergic Inflammation. The Journal of Immunology, 2006, 177 (12): 8633-8642