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Tracey Schock (Fed)

Tracey's research interests have focused on the intimate cyclic relationship of oceans and humans. Her backgrounds in marine science and molecular biology followed by a shift to marine natural products chemistry (dissertation work) have facilitated a seamless transition into her current research emphasis at NIST in the field of environmental metabolomics.

Metabolomics research is a quickly growing field with broad application and a likely long-lived future for the measure of physiology or health in real time. Tracey is applying this technique to investigate effects of environmental stressors, such as chemical exposure, disease and/or abiotic changes like rise of sea water temperature, which offers the opportunity to assess systematic responses at the organismal level. The research may result in identification of novel biochemistry, potential markers of stress, information about stressor mechanisms of action, and ultimately a monitoring tool for the health of the environment. The lab has conducted metabolomics studies on a variety of conditions and organisms including oxidative stress in crustaceans, temperature effect in the coral pathogen Vibrio coralliilyticus, alternative diets for aquaculture species, and illness in green sea turtles. Nuclear magnetic resonance (NMR) has been the primary analytical platform for these analyses with immediate plans for LC/MS-based analyses in upcoming studies.

Tracey's research has an overarching aim of promoting best practices to produce high quality metabolomics data which includes stringent experimental designs, efficient and repeatable metabolite extraction, and reproducible metabolite measurements. Her current metabolomic studies include health assessments of samples collected and banked with the Pacific Islands team of the NIST Marine Environmental Specimen Bank and toxicology studies with sentinel species

Membership and Professional Activities

  • Metabolomics Society
  • Society of Environmental Toxicology and Chemistry (SETAC)
  • American Chemical Society
  • Adjunct Appointments
    - The College of Charleston
    - The Medical University of South Carolina

Publications

Concordant inter-laboratory derived concentrations of ceramides in human plasma reference materials via authentic standards

Author(s)
Tracey Schock, Christina Jones, Federico Torta, Nils Hoffmann, Bo Burla, Irina Alecu, Makoto Arita, Takeshi Bamba, Steffany A.L. Bennett, Justine BERTRAND-MICHEL, Britta Brugger, Mónica Molina, María Dolores Camacho Muñoz, Antonio Checa, Michael Chen, Michelle Cinel, Benoit COLSCH, Cristina Coman, Bebiana Da Costa Sousa, Alex Dickens, Maria Maria, Finnur Freyr Eiríksson, Hector Gallart-Ayala, Mohan Ghorasaini, Martin Giera, Xue Guan, Mark Haid, Thomas Hankemeier, Amy Harms, Marcus Höring, Michal Holčapek, Thorsten Hornemann, Chunxiu Hu, Andreas Hülsmeier, Julijana Ivanisevic, Harald Köfeler, Sin Man Lam, Jong Cheol Lee, Gerhard Liebisch, Andrea F Lopez-Clavijo, Malena Manzi, Peter Meikle, Maria Monge, Sneha Muralidharan, Anna Nicolaou, Valerie O'Donnell, Matej Oresic, Arvind Ramanathan, Daisuke Saigusa, Heidi Schwartz-Zimmermann, Guanghou Shui, Masatomo Takahashi, Margrét Thorsteinsdóttir, Anthony Tournadre, Hiroshi Tsugawa, Victoria Tyrrell, Grace van der Gugten, Michael Wakelam, Craig Wheelock, Denise Wolrab, Guowang Xu, John Bowden, Kim Ekroos, Robert Ahrends, Markus Wenk
In this community effort, we compared measurements between 34 laboratories from 19 countries, utilizing mixtures of authentic synthetic standards, to quantify

Perspective: use and reuse of NMR‑based metabolomics data: what works and what remains challenging

Author(s)
Tracey Schock, Goncalo Gouveia, Thomas Head, Leo L. Cheng, Chaevian Clendinen, John Cort, Xiuxia Du, Edison Arthur, Candace Fleischer, Jeffrey C. Hoch, Nathaniel Mercaldo, Wimal Pathmasiri, Daniel Raftery, Lloyd Sumner, Panteleimon Takis, Valerie Copie, Hamid R. Eghbalnia, Robert Powers
The National Cancer Institute (NCI) issued a Request for Information (RFI) in October 2022, soliciting input on using and reusing metabolomics data. This RFI
Created August 15, 2019, Updated December 8, 2022