Stavis, S.
, Geist, J.
, Gaitan, M.
, Locascio, L.
and Strychalski, E.
(2011),
DNA ENTROPOPHORESIS: A BALANCE OF ENTROPY AND DIFFUSION IN COMPLEX NANOCONFINEMENT, DNA ENTROPOPHORESIS: A BALANCE OF ENTROPY AND DIFFUSION IN COMPLEX NANOCONFINEMENT, Seattle, WA, US
(Accessed December 4, 2024)
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DNA ENTROPOPHORESIS: A BALANCE OF ENTROPY AND DIFFUSION IN COMPLEX NANOCONFINEMENT
Published
Author(s)
, , , ,
Abstract
Entropophoresis - motion caused by an entropy gradient - is a novel nanofluidic method to direct the self-transport of biopolymers that established a new paradigm of nanofluidic functionality with broad relevance to lab-on-a-chip technol-ogy. Here, the entropic effects on size variation of DNA molecules descending a nanofluidic staircase by entropophoresis are studied. A simple numerical model provides insight into the behavior of confined biopolymers - a controversial topic of basic importance in many lab-on-a-chip applications - and informs the rational design and self-operation of nanofluidic devices for future entropophoretic applications, such as the directed self-separation of biomolecular mixtures and directed self-patterning of biomolecular concentration gradients.Proceedings Title
DNA ENTROPOPHORESIS: A BALANCE OF ENTROPY AND DIFFUSION IN COMPLEX NANOCONFINEMENT
Conference Dates
October 2-6, 2011
Conference Location
Seattle, WA, US
Conference Title
The 15th International Conference on Miniaturized Systems for Chemistry and Life sciences
Pub Type
Conferences
Keywords
Nanofluidics, DNA, Entropophoresis, Ideal chain, Polymer
Citation
Issues
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Created October 2, 2011, Updated October 12, 2021