Making digital phantoms with spectral and spatial light modulators for quantitative applications of hyperspectral optical medical imaging devices

Published

March 6, 2015

Author(s)

Bonghwan Chon, fuyuki Tokumasu, Ji Youn Lee, David W. Allen, Joseph P. Rice, Jeeseong C. Hwang

Abstract

We present a procedure to generate digital phantoms with a hyperspectral image projector (HIP) consisting of two liquid crystal on silicon (LCoS) spatial light modulators (SLMs). The digital phantoms are 3D image data cubes of the spatial distribution of spectrally resolved abundances of intracellular light-absorbing oxy-hemoglobin molecules in single erythrocytes. Spectrally and spatially resolved image data indistinguishable from the real scene may be used as standards to calibrate image sensors and validate image analysis algorithms for their measurement quality, performance consistency, and inter-laboratory comparisons for quantitative biomedical imaging applications.

Citation

SPIE Conference Proceedings

Volume

9325

Pub Type

Journals

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DOI Link

Keywords

Imaging system, medical optics, microscopy, imaging standard, spatial light modulator

Citation

Chon, B. , Tokumasu, F. , Lee, J. , Allen, D. , Rice, J. and Hwang, J. (2015), Making digital phantoms with spectral and spatial light modulators for quantitative applications of hyperspectral optical medical imaging devices, SPIE Conference Proceedings, [online], https://doi.org/10.1117/12.2085237 (Accessed January 2, 2025)