Robertson, J.
, Ghimire, M.
and Reiner, J.
(2021),
Nanopore sensing: a physical-chemical approach, Biochimica Et Biophysica ACTA-Biomembranes, [online], https://doi.org/10.1016/j.bbamem.2021.183644, https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=931550
(Accessed November 23, 2024)
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Nanopore sensing: a physical-chemical approach
Published
Author(s)
, Madhav Ghimire, Joseph Reiner
Abstract
Protein nanopores have emerged as an important class of sensor, for the understanding of biophysical processes, such as molecular transport across membranes, and detection and characterization of biopolymers. We trace the development of these sensors from the Coulter counter and squid axon studies through the modern applications of these sensors including exquisite detection of small volume changes and molecular reactions at the single molecule (or reactant) scale. The review focuses on the chemistry of biological pores, and how that influences the physical chemistry of molecular detection.Citation
Biochimica Et Biophysica ACTA-Biomembranes
Volume
1863
Issue
9
Pub Type
Journals
Download Paper
Keywords
nanopore sensor, ion channel, porin, DNA sequencing, peptide detection
Citation
Issues
If you have any questions about this publication or are having problems accessing it, please contact reflib@nist.gov.
Created September 1, 2021, Updated May 26, 2021