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NIST Authors in Bold

Displaying 251 - 275 of 1174

Microscopic Identification of Micro-Organisms on Pre-Viking Swedish Hillfort Glass

September 30, 2018
Author(s)
Bruce Arey, Edward Vicenzi, Rolf Sjoblom, Robert Koestler, Paula DePriest, Thomas Lam, David Peeler, John McCloy, Albert Kruger, Jamie Weaver
Borborg Hillfort is a vitrified hillfort located in the Husby-Långhundra parish in Uppland Sweden (Fig. 1A). The site dates to the Great Migration Period, around 740 ± 100 CE. [1]. Two types of glasses have been identified within the ramparts – one that is

Methodology for evaluating and comparing fluorescence measurement capabilities: Multi-site study of 23 flow cytometers

September 23, 2018
Author(s)
David R. Parks, Wayne A. Moore, Ryan Brinkman, Yong Chen, Danilo Condello, Faysal E. Khettabi, John P. Nolan, Stephen P. Perfetto, Doug Redelman, Josef Spidlen, Jonathan V. Dyke, Lili Wang, James C. Wood
We developed measurement methods and analysis procedures to perform inter-instrument comparisons and used them to evaluate and compare the fluorescence measurement capabilities among 23 cytometers in 9 laboratories selected to provide a range of

Structure of the Fc Fragment from the NIST Reference Antibody RM8671

September 1, 2018
Author(s)
David Travis Gallagher, Connor V. Galvin, Ioannis Karageorgos
As the link between antigen binding and immune activation, the antibody Fc region has received extensive structural study. In this report, the structure of the Fc fragment of the NIST IgG1 mAb (reference material 8671) is described at 2.1 Å resolution in

High-speed alignment optimization of digital optical phase conjugation systems based on autocovariance analysis in conjunction with orthonormal rectangular polynomials

August 28, 2018
Author(s)
Ashton S. Hemphill, Yuecheng Shen, Jeeseong C. Hwang, Lihong V. Wang
Digital optical phase conjugation (DOPC) enables many optical applications by permitting focusing of light through scattering media. However, DOPC systems require precise alignment of all optical components, particularly of the spatial light modulator (SLM

Conference Report: Representing Ethnic Diversity for Precision Medicine

August 23, 2018
Author(s)
Justin M. Zook, Luke Hickey, Benedict Paten, Robert Sebra, Valerie Schneider
There is a pressing need to better represent ethnic diversity with genomic resources — and to do so in a way that maximizes utility for people working with the Genome Reference Consortium’s human reference genome. That was the theme of a panel discussion

A radial calibration window for analytical ultracentrifugation

July 20, 2018
Author(s)
Thomas W. LeBrun, Peter Schuck, Wei Ren, Justine Yoon, Xianghui Dong, Nicole Y. Morgan, Jeffrey Fagan, Huaying Zhao
Analytical ultracentrifugation (AUC) is a first-principles based method for studying particles in solution by monitoring the evolution of their radial concentration distribution as a function of time in the presence of a high centrifugal field. In

NIST Spectroscopic Measurement Standards

May 1, 2018
Author(s)
Paul C. DeRose, Kenneth D. Cole, Aaron Urbas, Steven J. Choquette, Evelyn Solis, Erica V. Stein, John E. Schiel, Brian Lang, Hua-Jun He
Ultraviolet (UV) absorbance measurements provide a rapid and reliable method to determine protein concentrations. The National Institute of Standards and Technology (NIST) has developed Standard Reference Material (SRM) 2082as a pathlength standard for UV

Oxidatively-induced DNA damage and base excision repair in euthymic patients with bipolar disorder

May 1, 2018
Author(s)
Deniz Ceylan, Gamze Tuna, Guldal Kirkali, Zeliha Tunca, Gunes Can, Hidayet E. Arat, Melis Kant, Miral M. Dizdar, Aysegul Ozerdem
Oxidatively-induced DNA damage has previously been associated with bipolar disorder. More recently, impairments in DNA repair mechanisms have also been reported. We aimed to investigate oxidatively-induced DNA lesions and expression of DNA glycosylases

Perfluorinated Alkyl Acids and Fecundity Assessment in Striped mullet (Mugil cephalus) at Merritt Island National Wildlife Refuge

April 1, 2018
Author(s)
John Bowden, Jacqueline T. Bangma, Jessica L. Reiner, Russell H. Lowers, Theresa M. Cantu, Jacob Scott, Jeffery Korte, Douglas M. Scheidt, Chris McDonough, Jonathan Tucker, Eric Reyier, Douglas H. Adams, Bonnie Ahr, Brenton Back
This study investigated wild caught Striped mullet (Mugil cephalus) at Merritt Island National Wildlife Refuge (MINWR) for levels of 15 perfluoroalkyl acids (PFAAs) in tandem with fecundity measurements (n = 42) and oocyte developmental stages (n = 128)

Qualification of NISTmAb charge heterogeneity control assays

March 18, 2018
Author(s)
Abigail Turner, John E. Schiel
The NISTmAb is a monoclonal antibody Reference Material from the National Institute of Standards and Technology; it is a class-representative IgG1κ intended serve as a pre-competitive platform for harmonization and technology development in the

Development of an LC-MS/MS peptide mapping protocol for the NISTmAb

March 1, 2018
Author(s)
Catherine A. Mouchahoir, John E. Schiel
Peptide mapping is a component of the analytical toolbox used within the biopharmaceutical industry to aid in the identity confirmation of a protein therapeutic and to monitor degradative events such as oxidation or deamidation. These methods offer the

FEASST: Free Energy and Advanced Sampling Simulation Toolkit

March 1, 2018
Author(s)
Harold W. Hatch, Nathan Mahynski, Vincent K. Shen
The Free Energy and Advanced Sampling Simulation Toolkit (FEASST) is a free, open-source, modular program to conduct molecular and particle-based simulations with Metropolis, Wang-Landau and Transition-Matrix Monte Carlo methods. FEASST is implemented in C

Examining Heat Treatment for Stabilization of the Lipidome

February 16, 2018
Author(s)
John Bowden, Candice Z. Ulmer, Christina Jones, Tracey Johnston, Jeremy P. Koelmel, Timothy J. Garrett, Richard A. Yost
Aim: To confidently determine lipid-based biomarkers, it is important to minimize variation introduced during preanalytical steps. We evaluated reducing variation associated with lipid measurements in invertebrate sentinel species using a state-of-the-art

forum Update May 31 2017

January 30, 2018
Author(s)
Carl G. Simon Jr.
Advanced Regenerative Manufacturing Institute (ARMI) The Department of Defense has announced an award of $80M to the non-profit Advanced Regenerative Manufacturing Institute (ARMI) located in Manchester, NH, led by Dean Kamen: www.armiusa.org. This award
Displaying 251 - 275 of 1174