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Displaying 526 - 550 of 837

Characterization of Hyperspectral Imaging and Analysis via Microarray Printing of Dyes

February 22, 2011
Author(s)
Matthew L. Clarke, Maritoni A. Litorja, David W. Allen, Daniel V. Samarov, Jeeseong Hwang
The application of hyperspectral imaging requires rigorous characterization of the spatial and spectral imaging domains of the system. We present a microarray printing methodology for the testing of absorption or reflectance microscopy measurements. This

The Lung Image Database Consortium (LIDC) and Image Database Resource Initiative (IDRI): A Completed Reference Database of Lung Nodules on CT Scans

January 28, 2011
Author(s)
Charles D. Fenimore, Samuel Armato, Denise Aberle, Matthew Brown, Claudia Henschke, Michael McNitt-Gray, Heber MacMahon, Geoffrey McLennan, Charles R. Meyer, Anthony P. Reeves, David F. Yankelevitz
The development of computer-aided diagnostic (CAD) methods for lung nodule detection, classification, and quantitative assessment can be facilitated through a well-characterized repository of computed tomography scans. The Lung Image Database Consortium

NMR Characterization of the Formation Kinetics and Structure of Di-O-Benzylidene Sorbitol Gels Self-Assembled in Organic Solvents

January 19, 2011
Author(s)
David L. VanderHart, Jack F. Douglas, Steven Hudson, Joseph M. Antonucci, Elizabeth A. Wilder
The molecule 1,3:2,4-Di-O-Benzylidene sorbitol (DBS) is a common gelator that forms thermally reversible gels in diverse organic solvents. Solid state 13C and proton NMR techniques, along with electron microscopy, are utilized in an exploratory study of

On-chip CO2 control for microfluidic cell culture

January 1, 2011
Author(s)
Samuel P. Forry, Laurie E. Locascio
Carbon dioxide partial pressure (PCO2) was controlled on-chip by flowing pre-equilibrated aqueous solutions through control channels across the device. Elevated PCO2 (e.g. 0.05 atm) was modulated in neighboring stagnant channels via equilibration through

Predicting Segmentation Accuracy for Biological Cell Images

December 15, 2010
Author(s)
Adele P. Peskin, Alden A. Dima, Joe Chalfoun, John T. Elliott
We have performed segmentation procedures on a large number of images from two mammalian cell lines that were seeded at low density, in order to study trends in the segmentation results and make predictions about cellular features that affect segmentation

Predicting Segmentation Accuracy for Biological Cell Images

November 29, 2010
Author(s)
Adele P. Peskin, Alden A. Dima, Joe Chalfoun
We have performed image segmentations on a very large number of images, using a wide variety of imaging conditions and cell lines, in order to study trends in the segmentation results and make predictions about segmentation accuracy. Comparing results from

A Human Inspired Local Ratio-Based Algorithm for Edge Detection in Fluorescent Cell Images

November 25, 2010
Author(s)
Adele P. Peskin, Joe Chalfoun, Alden A. Dima, John T. Elliott, James J. Filliben
We have developed a new semi-automated method for segmenting images of biological cells seeded at low density on tissue culture substrates, which we use to improve the generation of reference data for the evaluation of automated segmentation algorithms

Effect of 3D Hydrogel Scaffold Stiffness on Human Bone Marrow Stromal Cell Differentiation

November 1, 2010
Author(s)
Carl G. Simon Jr., Sapun Parekh, Marcus T. Cicerone, Sheng Lin-Gibson, Kaushik Chatterjee, Marian F. Young
There is growing recognition cells can sense and respond to the mechanical properties of tissue scaffolds and that these interactions are critical in optimizing scaffold design [1-4]. Previous studies in planar 2D culture format have shown that human bone

An Advanced Patient Lift and Transfer Device for the Home

October 29, 2010
Author(s)
Roger V. Bostelman, Ji-Chul Ryu, Tommy Chang, Joshua Johnson, S K. Agrawal
The Home Lift, Position and Rehabilitation (HLPR) Chair has a unique design and novel capabilities when compared to conventional powered wheelchairs. In addition to mobility, it provides lift and can transfer patients. Even though medical devices are

International Comparability in Circular Dichroism: II

October 4, 2010
Author(s)
Curtis W. Meuse, Jascindra Ravi, Paulina Rakowska, Tommaso Garfagnini, Alex E. Knight, Philippe Charlet, Julie D. Lorenz, Christopher Jones, David F. Plusquellic, Frank Wien, Liqing Wu
A previous inter-laboratory study, CCQM P59, showed that there was a poor level of comparability between laboratories in circular dichroism spectroscopy. In a follow-up study reported here, we achieved our goal of demonstrating improved comparability and

Nanoslinky: DNA Entropophoresis Down a Nanofluidic Staircase

October 4, 2010
Author(s)
Elizabeth A. Strychalski, Laurie E. Locascio, Samuel M. Stavis, Michael Gaitan
Almost all nanofluidic devices for biopolymer analysis have been limited by one or two confining structural dimen-sions or the application of external forces for biopolymer manipulation, which has restricted the scope of related lab-on-a-chip technology
Displaying 526 - 550 of 837