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Displaying 126 - 150 of 1719

Tissue Engineering Measurands

August 26, 2020
Author(s)
Greta Babakhanova, Carl Simon Jr., Deepika Arora
A measurand is defined as the quantity that one intends to measure. As tissue engineering research translates into medical products, companies must prepare regulatory filings that contain many different types of measurement data that are collected about

Improving patient outcomes with regenerative medicine: How to move the needle forward in cell manufacturing, standards, 3D bioprinting, AI enabled automation, education and training

June 17, 2020
Author(s)
Carl Simon Jr., Josh Hunsberger, Claudia Zylberberg, Preveen Ramamoorthy, Thomas Tubon, Crystal Ruff, Ram Bedi, Kurt Gielen, Lynn Fisher, Jed Johnson, Priya Barankiak, Behzad Mahdavi, Michael Hadjisavas, Shannon Eaker, Cameron Miller
Regenerative Medicine Manufacturing Society (RMMS), is the first and only professional society dedicated specifically towards advancing manufacturing solutions for the field of regenerative medicine. RMMS' vision is to provide greater patient access to

A Tool to Model the Fate and Transport of Indoor Microbiological Aerosols (FaTIMA)

June 1, 2020
Author(s)
William S. Dols, Brian J. Polidoro, Dustin G. Poppendieck, Steven J. Emmerich
The web-based tool Fate and Transport of Indoor Microbiological Aerosols (FaTIMA) allows for the determination of the indoor fate of microbiological aerosols associated with ventilation, filtration, deposition and inactivation mechanisms. FaTIMA provides a

Quantitative Bright-Field Microscopy Combined with Deep Neural Networks Predict Live Tissue Function

February 29, 2020
Author(s)
Carl Simon Jr., Nicholas J. Schaub, Petru S. Manescu, Sarala Padi, Mylene Simon, Peter Bajcsy, Nathan A. Hotaling, Joe Chalfoun, Mohamed Ouladi, Qin Wan, Kapil Bharti, Ruchi Sharma
Progressive increases in the number of cell therapies in the preclinical and clinical phases has prompted the need for reliable and non-invasive assays to validate transplant function in clinical biomanufacturing. Here, we developed a robust

The Reproducibility of a Proposed Standard Fatigue Test for Cardiac Device Leads

August 1, 2019
Author(s)
Timothy P. Quinn, Jolene D. Splett, Joseph D. McColskey, James Dawson, David Smith, Adam Himes, Daniel Cooke
The Transvenous Cardiac Leads Working Group of the Cardiac Rhythm Management Devices Committee of The Association for the Advancement of Medical Instrumentation (AAMI CRMD WG1) is developing a fatigue performance standard for cardiac device leads. The

A Novel Dental Sealant Containing Dimethylaminohexadecyl Methacrylate Suppresses the Cariogenic Pathogenicity of Streptococcus mutans Biofilms

July 16, 2019
Author(s)
Nancy Lin, Maria S. Ibrahim, Ahmed Ibrahim, Abdulrahman Balhaddad, Michael D. Weir, Franklin Tay, Thomas Oates, Hockin H. Xu, Mary A. Melo
Cariogenic oral biofilms are strongly linked to dental caries around dental sealants. Quaternary ammonium monomers copolymerized with dental resin systems have been increasingly explored for modulation of biofilm growth. Here, we investigated the effect of

Structural Insights into DNA-Stabilized Silver Clusters

May 10, 2019
Author(s)
Danielle Schultz, Robert G. Brinson, Fahriye N. Sari, Jeffrey Fagan, Christina Bergonzo, Nancy Lin, Joy Dunkers
The structure and dynamics of Ag complexes derived from single stranded DNA (ssDNA) is less understood than their double stranded (dsDNA) counterparts despite their great promise as fluorescent biological probes and sensors. In this work, we seek new

Targeting hMSC Response via Surface Carbonyl Groups, Contact Angle, and Protein Interactions

March 1, 2019
Author(s)
Max J. Lerman, Shinichiro Muramoto, Navein Arumugasaamy, Michael Van Order, Josephine Lembong, Anushka Gerald, John G. Gillen, John P. Fisher
Traditional 2D culture systems made of polystyrene (PS) require the addition of surface chemistry beyond the nominal phenyl groups present to facilitate and encourage cell adhesion. Determining the surface properties which enhance protein adhesion from

Mechanosensitive ion permeation across sub-nanoporous MoS2 monolayers

January 23, 2019
Author(s)
Alta Y. Fang, Kenneth Kroenlein, Alex Smolyanitsky
We use all-atom molecular dynamics simulations informed by density functional theory calculations to investigate aqueous ion transport across subnanoporous monolayer molybdenum disulfide (MoS2) membranes subject to varying tensile strains. Driven by a
Displaying 126 - 150 of 1719