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Displaying 201 - 225 of 242

Oxidative DNA Damage and Its Potential Use for Monitoring Oxidative Stress

September 1, 2000

Author(s)

M. Dizdaroglu

Immobilization of Nucleic Acids at Solid Surfaces: Effect of Oligonucleotide Length on Layer Assembly

August 1, 2000

Author(s)

A B. Steel, R Levicky, T M. Herne, Michael J. Tarlov

This report investigates the effect of DNA length and the presence of an anchoring group on the assembly of pre-synthesized oligonucleotides at a gold surface. The work seeks to advance fundamental insight into issues that impact the structure and behavior

Oxidative DNA Damage; Mechanisms of Product Formation and Repair By Base-Excision Pathway

May 1, 2000

Author(s)

M Miral Dizdar

Free radicals such as OH, e aq- and H atoms react with DNA by addition to bases or abstraction of H atoms from the sugar moiety. Oxygen adds to base or sugar radicals of DNA resulting in formation of peroxyl radicals. DNA radicals further react to give

Human Mitochondrial Genetics

January 1, 2000

Author(s)

L A. Tully, Barbara C. Levin

The field of human mitochondrial genetics has advanced way beyond where the Human Genome Project hopes to be by the year 2003, the projected year for completing the sequence of the entire human nuclear DNA genome. Not only has the mitochondrial DNA (mtDNA)

Mapping Oxidative DNA Damage and Mechanisms of Repair

January 1, 2000

Author(s)

H Rodriguez, T. O'Connor, S. A. Akman

Effects of NiII and CuII on DNA Interaction with the N-terminal Sequence of Human Protamine P2: Enhancement of Binding and Mediation of Oxidative DNA Strand Scission and Base Damage

December 1, 1999

Author(s)

R Liang, S. Senturker, X Shi, W Bal, M. Dizdaroglu, K S. Kasprzak

J-Coupling Restraints in RNA Structure Determination

December 1, 1999

Author(s)

John P. Marino, H Schwalbe, C Griesinger

Mapping Reactive Oxygen-Induced DNA Damage at Nucleotide Resolution

December 1, 1999

Author(s)

S. A. Akman, R Drouin, G P. Holmquist, H Rodriguez

Measurement of Oxidatively Induced Base Lesions in Liver Nuclear and Mitochodrial DNA from Wistar Rats of Different Ages

December 1, 1999

Author(s)

R M. Anson, S. Senturker, Miral M. Dizdar, V A. Bohr

Mechanisms of Oxidative DNA Damage; Lesions and Their Measurement

December 1, 1999

Author(s)

M. Dizdaroglu

Repair of Oxidative DNA Base Lesions Induced by Fluorescent Light is Defective in Xeroderma Pigmentosum Group A Cells

December 1, 1999

Author(s)

L J. Lipinski, N Hoehr, S J. Mazur, G Dianov, S. Senturker, M. Dizdaroglu, V A. Bohr

Results from the 1999 NIST Mixed-Stain Study #2 DNA Quantitation, Differential Extraction and Identification of the Unknown Contributors

September 1, 1999

Author(s)

Margaret C. Kline, Janette W. Redman, David L. Duewer, D J. Reeder

The National Institute of Standards and Technology (NIST) has provided a number of educational interlaboratory exercises to the forensic community. The recent NIST Mixed Stain Study #2 consisted of three separate sets of materials. Set 1) three stains on