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Search Publications by: Jeeseong C. Hwang (Fed)

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Displaying 51 - 75 of 171

Making digital phantoms with spectral and spatial light modulators for quantitative applications of hyperspectral optical medical imaging devices

March 6, 2015
Author(s)
Bonghwan Chon, fuyuki Tokumasu, Ji Youn Lee, David W. Allen, Joseph P. Rice, Jeeseong C. Hwang
We present a procedure to generate digital phantoms with a hyperspectral image projector (HIP) consisting of two liquid crystal on silicon (LCoS) spatial light modulators (SLMs). The digital phantoms are 3D image data cubes of the spatial distribution of

An Average Enumeration Method of Hyperspectral Imaging Data for Quantitative Evaluation of Medical Device Surface Contamination

September 15, 2014
Author(s)
Hanh Le, Moon Kim, Jeeseong C. Hwang, Yi Yang, Pawneena U-Thainual, Jin Kang, Do-Hyun Kim
We propose a quantification method called Mapped Average Principal component analysis Score (MAPS) to enumerate the contamination coverage on common medical device surfaces. The method was adapted from conventional Principal Component Analysis (PCA) on non

A Candidate Reference Analytical Method for Quantification of Low Concentrations of Plasmid DNA by Exhaustive Counting of Single DNA Molecules in a Flow Stream

August 4, 2014
Author(s)
Hee-Bong Yoo, Dong-Geun Oh, Jae Yong Song, Mamoru Kawaharasaki, Jeeseong C. Hwang, In Chul Yang, Sang-Ryoul Park
This work demonstrates accurate measurement of the concentration of low-level plasmid DNA by counting individual DNA molecules using a high-sensitivity flow cytometric setup. Plasmid DNA is a widely used form of DNA, and its quantity often needs to be

Optical Coherence Tomography for Dimensional Metrology of Lab-on-a-chip devices

October 27, 2013
Author(s)
Darwin R. Reyes-Hernandez, Michael W. Halter, Jeeseong Hwang
Here we present a new metrology tool for the determination of the dimensions of channels from final product Lab-on-a-chip devices. Using Optical Coherence Tomography (OCT) areas of up to 12 mm x 12 mm can be imaged in less than 1 second, without the need

Mapping the Vif-A3G interaction using peptide arrays: a basis for anti-HIV lead peptides

June 15, 2013
Author(s)
Jeeseong Hwang, Ji Y. Lee, Abigail E. Miller, Tali Reingewertz, Elena Britan-Rosich, Shahar Rotem-Bamberger, Mathias Viard, Robert Blumenthal, Assaf Friedler
Human apolipoprotein-B mRNA-editing catalytic polypeptide-like 3G (A3G) is a cytidine deaminase that restricts retroviruses, endogenous retro-elements and DNA viruses. A3G plays a key role in the anti- HIV-1 innate cellular immunity. The HIV-1 Vif protein

Metrology for Lab-on-a-Chip Final-Product Devices

May 12, 2013
Author(s)
Darwin R. Reyes-Hernandez, Michael W. Halter, Jeeseong Hwang
New metrology tools to measure the critical parameters of internal structures in lab on a chip devices are greatly needed in order to develop standard tests for this technology. Here we present a method that combines a custom made optical coherence

Developing digital tissue phantoms for hyperspectral imaging of ischemic wounds

May 18, 2012
Author(s)
David W. Allen, Jeeseong Hwang, Maritoni A. Litorja, Joseph P. Rice
Biomedical optical imaging has the potential to achieve high spatial resolution and high functional sensitivity for non-invasive assessment of ischemic wounds. However, clinical acceptance of many optical imaging devices is hampered by poor reproducibility

Algorithm Validation Using Multicolor Phantoms

May 9, 2012
Author(s)
Daniel V. Samarov, Matthew L. Clarke, Ji Y. Lee, David W. Allen, Maritoni A. Litorja, Jeeseong Hwang
We present a framework for hyperspectral image (HSI) analysis validation, specifically abundance fraction estimation based on HSI measurements of water soluble dye mixtures printed on microarray chips. In our work we focus on the performance of two