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Search Publications by: Young Jong Lee (Fed)

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Displaying 26 - 50 of 79

Raman Identification of Multiple Melting Peaks of Polyethylene

August 1, 2017
Author(s)
Ying Jin, Anthony P. Kotula, Chad R. Snyder, Angela R. Hight Walker, Kalman D. Migler, Young J. Lee
Multiple melting peaks of high-density polyethylene produced by complex thermal pre-treatment are investigated with variable temperature Raman spectroscopy and differential scanning calorimetry (DSC). We examine the origin of the observed multiple melting

Dielectric Spectroscopy During Extrusion Processing of Polyamide-6 Nanocomposites

February 19, 2017
Author(s)
Rick D. Davis, Anthony J. Bur, Jeffrey W. Gilman, Young Jong Lee, P R. Start
During extrusion processing dielectric spectroscopy was conducted on polyamide-6 (PA6) and organoclay/polyamide-6 nanocomposites. Off-line curve fitting of the on-line dielectric data generated dielectric dispersion parameters that appear sensitive to

Least Squares Moving-Window Spectral Analysis

January 20, 2017
Author(s)
Young J. Lee
Least squares regression is proposed as a moving-windows method for analysis of a series of spectra acquired as a function of external perturbation. The least squares moving-window (LSMW) method can be considered an extended form of the Savitzky–Golay

Beam-Scanning for Rapid Coherent Raman Hyperspectral Imaging

December 14, 2015
Author(s)
Seungwan Ryu, Charles Camp, Ying Jin, Marcus T. Cicerone, Young Jong Lee
Coherent Raman imaging requires high peak power laser pulses to maximize the nonlinear multiphoton signal generation, but accompanying photo-induced sample damage often poses a challenge to microscopic imaging studies. We demonstrate that a beam-scanning

Quantitative, label-free characterization of stem cell differentiation at the single-cell level by broadband coherent anti-Stokes Raman scattering microscopy

December 31, 2014
Author(s)
Marcus T. Cicerone, Young J. Lee, Khaled A. Aamer, Prabhas V. Moghe, Sebastian L. Vega, Parth J. Patel
We use broadband coherent anti-Stokes Raman scattering (BCARS) microscopy to characterize lineage commitment of individual human mesenchymal stem cells (hMSCs) cultured in adipogenic, osteogenic, and basal culture media. We treat hyperspectral images

High-Speed Coherent Raman Fingerprint Imaging of Biological Tissues

July 20, 2014
Author(s)
Charles H. Camp, Young J. Lee, John M. Heddleston, Christopher M. Hartshorn, Angela R. Hight Walker, Jeremy N. Rich, Justin D. Lathia, Marcus T. Cicerone
We have developed a coherent Raman imaging platform using broadband coherent anti-Stokes Raman scattering (BCARS) that provides an unprecedented combination of speed, sensitivity, and spectral breadth. The system utilizes a unique configuration of laser

Multicomponent Chemical Imaging of Pharmaceutical Solid Dosage Forms with Broadband CARS Microscopy

July 15, 2013
Author(s)
Christopher M. Hartshorn, Marcus T. Cicerone, Young J. Lee, Charles H. Camp, John M. Heddleston, Patrick Marsac, Tim Rhodes, Zhen Liu, Nicole Canfield
We compare broadband coherent anti-Stokes Raman scattering (BCARS) microscopy with spontaneous Raman microscopy for quantitative and qualitative assessment of multicomponent pharmaceuticals. Indomethacin was used as a model active pharmaceutical ingredient