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Search Publications by: Tim Quinn (Fed)

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Displaying 26 - 50 of 71

Prediction of Collagen and Glycosaminoglycan Content by Acoustic Microscopy

April 21, 2010
Author(s)
Jenni R. Popp, Colm Flannery, Tammy L. Oreskovic, Jennifer Recknor, Kristi S. Anseth, Timothy P. Quinn
Functional tissue engineering of articular cartilage is rapidly advancing as a technique to develop regenerative and reparative treatments for cartilage degeneration and osteoarthritis. Tissue engineered constructs are often developed using a combination

Tissue Engineered Scaffolds for Screening Nanoparticle - Cell Interactions

April 21, 2010
Author(s)
Kavita M. Jeerage, Elisabeth Mansfield, Tammy L. Oreskovic, Nikki S. Rentz, Timothy P. Quinn
Long-term studies of nanoparticle-cell interactions require an advanced tissue-like environment in which nanoparticles are encapsulated with a population of cells for real-time and end-point analysis. By using soft tissue-mimicking hydrogels, the cells are

An Instrumented Bioreactor for Cartilage Tissue Engineering

April 29, 2009
Author(s)
Timothy P. Quinn, Colm Flannery, Damian S. Lauria, Douglas V. Gallagher, Kristi S. Anseth
Bioreactors for in vitro growth of engineered tissue (ET) would ideally include sensors that would continuously measure the functional quality of the construct during incubation. Principles of feedback control could then be used to optimize properties of

Evaluation of Polydimethylsiloxane Modification Methods for Cell Response

February 20, 2009
Author(s)
Lisa Pakstis, Alan Zheng, Theodore V. Vorburger, Joy P. Dunkers, Timothy P. Quinn, Marcus T. Cicerone
Many methods exist in the literature to modify surfaces with extracellular matrix (ECM) proteins prior to cell attachment. However, there are few studies that systematically compare surface characterization and cell response results among different

Stiffening of the Extrapulmonary Arteries in Chronic Hypoxic Pulmonary Hypertension

July 1, 2008
Author(s)
Elizabeth S. Drexler, J. E. Bischoff, Christopher N. McCowan, Andrew Slifka, Timothy P. Quinn, R Shandas, Dunbar Ivy, K. R. Stenmark
It is increasingly appreciated that changes in the compliance properties of large blood vessels are critical determinants of ventricular afterload and ultimately dysfunction. Little is known of the mechanical properties of large vessels in the setting of

Investigations into the potential contribution of a thermal mechanism for pulsed-high intensity focused ultrasound mediated delivery

December 3, 2007
Author(s)
Brian E. O'Neill, Howard Vo, Mary Angstadt, Victor Frenkel, Bradford Wood, Timothy P. Quinn
The mechanism behind pulsed high intensity focused ultrasound (pHIFU) effects leading to increased drug delivery are currently poorly understood. In this work, the thermal dose and peak temperatures associated with a typical pHIFU treatment were measured

Dynamic Factors Contributing to Buckling and Birdnesting During GMAW Wire Feeding

June 1, 2005
Author(s)
Toby Padilla, Timothy P. Quinn, D. R. Munoz, R. A. Rorrer, John R. Berger
This study provides experimental data for determining the factors affecting wire feeding performance. Full-scale experiments show that feeding performance, in terms of wire feed speed and wire feeding force, varies with the material system and with the

A Coupled Arc and Droplet Model of GMAW

January 8, 2005
Author(s)
Timothy P. Quinn, M Szanto, T Gilad, I Shai
A model of gas metal arc welding was developed that solves the magneto-hydrodynamic equations for the flow and temperature fields of the molten electrode and the plasma simultaneously, to form a fully coupled model. A commercial finite element code was