Terahertz Spectroscopy of Short-Chain Polypeptides

Published

July 1, 2003

Author(s)

M R. Kutteruf, Craig Brown, L K. Iwaki, M B. Campbell, Timothy M. Korter, Edwin J. Heilweil

Abstract

Terahertz (THz) absorption and neutron vibrational spectra for solid-phase short-chain peptide sequences at 77 K and 298 K are reported. We demonstrate that a high degree of spectral and structural information exists for these systems in the 1 THz to 15 THz (33 cm^-1 to 500 cm^-1) spectral range. The density and uniqueness of distinct spectral features for each system suggests that sequence-dependent structural information can potentially be extracted from these spectra using quantum mechanical solid-state modeling and theories.

Citation

Chemical Physics Letters

Volume

375

Issue

No. 3-4

Pub Type

Journals

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Keywords

ab-initio calculations, crystal structure, far infrared, molecular modeling, neutron spectroscopy, peptides, sequencing, solid-state samples, terahertz spectroscopy

Citation

Kutteruf, M. , Brown, C. , Iwaki, L. , Campbell, M. , Korter, T. and Heilweil, E. (2003), Terahertz Spectroscopy of Short-Chain Polypeptides, Chemical Physics Letters, [online], https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=841701 (Accessed July 17, 2024)