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Biological physics

News and Updates

Projects and Programs

Measurement Techniques for Membranes and Membrane Proteins

Ongoing
Use of synthetic cell membrane mimics allow simplification and complete control of a complicated system, and incorporation of selected elements under physiological conditions. We are furthering a technology originally developed at NIST using model lipid membranes supported on surfaces for

State-resolved Spectroscopy of Biomolecules

Ongoing
Terahertz radiation interrogates the lowest frequency vibrational modes of a biomolecule. These modes characterize the incipient motions for large-scale conformational changes responsible for the backbone flexibility of protein, polynucleotide and polysaccharide. Thus, terahertz spectral features

Label-free imaging of cells and their extracellular matrix by SPR imaging

Ongoing
Cellular remodeling of their neighboring environment, extracellular matrix (ECM), is an important biological process from development biology, to wound healing, to diseases and cancers – this is a challenging process to measure and quantify. Surface plasmon resonance imaging (SPRI) has been

Publications

Software

MOSAIC

MOSAIC is a modular single-molecule analysis toolbox to decode multi-state single-molecule and nanopore time-series data. Read the documentation for additional