U.S. flag

An official website of the United States government

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

Material Measurement Laboratory

Projects/Programs

Displaying 26 - 50 of 560
nanoparticle model

Assessing the Environmental, Health and Safety Impact of Nanoparticles

Completed
Impact Nanomaterials have already been incorporated into a large range of commercial products including pharmaceuticals, sunscreens, automobile additives, personal care products, detergents and plastics. Although nanotechnology is changing the way we live, the accidental release of nanomaterials

Assessment of Uncertainty in CALPHAD Descriptions

Ongoing
Knowledge of phase equilibria and phase transformations is absolutely essential for the development of new materials and processing methods. The CALPHAD (CALculation of PHAse Diagrams) method is a proven, indispensable tool in this endeavor. It combines thermodynamic descriptions of binary and

Atomistic Potentials and the Future of Nanomaterials Metrology

Ongoing
Atomistic simulations are increasingly being used as a tool to understand and predict properties of materials in systems, such as nanomaterials, where direct measurement is time-consuming or extremely difficult. The success of atomistic simulations depends critically on the fidelity of a specific

Atomistic tools for structure-property investigations

Ongoing
Interatomic Potential Repository The Interatomic Potentials Repository (IPR) provides a source for interatomic potentials (force fields), related files, and evaluation tools to help researchers obtain interatomic models and judge their quality and applicability. The files provided are of known
Photograph of gas cylinders

Audit of EPA Protocol Gas Suppliers

Ongoing
Protocol gas standards are employed in measurements made for compliance purposes; one of the major uses is for measurements of regulated gaseous species from stationary source emitters, i.e., stack gases. Many of these stationary sources are regulated through the Cap and Trade program; therefore

Automation for Atomistic Simulation

Ongoing
In computational materials science, many problems require the execution of numerous parallel simulation tasks on High Performance Computing (HPC) resources. Often a single published data point is the result of several parallel tasks executed in a specific sequence. Despite the continual improvement

Automotive Lightweighting

Ongoing
The US auto industry spends $600M per year fixing and tweaking forming dies that do not make correct parts. The primary reason that the dies are inaccurate is that the computer models of the dies utilize materials models that are inaccurate. Upon surveying our industrial partners, we determined that
schematic of the scanning droplet cell apparatus

Autonomous Scanning Droplet Cell

Ongoing
Corrosion impacts a broad spectrum of application areas including infrastructure, transportation, and the military. The annual price tag for corrosion mitigation and remediation is 3.4 % of the US GDP. The team is particularly interested in discovering new metallic glasses (metals without long range
Streptococcus mutans

Biofilm Models to Evaluate Structure-Function Relationships

Ongoing
Biofilms are complex 3D microbial structures that exist throughout nature including on our skin and gut mucosa, in waterways, and in soil. They are typically composed of multiple microbial species surrounded by proteins, polysaccharides, and extracellular DNA woven together into a hydrated matrix

Bioimaging

Completed
Imaging and image analysis are used ubiquitously in biological and biomedical research. One of the great advantages of imaging is its intuitive information content; much can be learned from just a glance at the data. On the other hand, these data generally contain a very large amount of untapped
Bioman lifecycle

Biomanufacturing Initiative

Ongoing
The objective of the NIST biomanufacturing program is to support US biopharmaceutical industry delivery of high quality and low cost protein drugs around the world. The mission is fulfilled through the development of standards, measurement science, and state of the art tools that support advances in

Biomaterials for Oral Health

Completed
NIST along with its partners has a long commitment to scientific excellence with demonstrated impact in improving the oral health of the public. NIST researchers are leaders in this field and create a community by engaging other researchers, industry, and regulatory agencies to address urgent needs

Bioprocessing Laboratory

Ongoing
Current Capabilities Computer controlled liquid nitrogen biostorage system Two culture areas including 4 monitored CO2 incubators 2 Six-foot BSLII biosafety cabinets Measurements- cell count and concentration, STR typing, flow cytometry, cell volume size distribution, conventional transmission and
Genetic codes

Biosecurity for Synthetic Nucleic Acid Sequences

Ongoing
Emerging biotechnology, enabled by the ability to genetically engineer biological systems similar to the way we write software and program computers, can provide solutions to many pressing societal needs related to health, food security, supply chain resilience, and job growth for economic and

Biosurveillance and Pathogen Detection

Ongoing
NIST has established partnerships with other federal agencies to develop standards and measurement solutions to support biosurveillance. These efforts are supported in part through interagency agreements with partner agencies listed below to address their standards needs. PROGRAMS Standards for
Long_Feature_Image

Bringing the SI to Global Atmospheric Greenhouse Gas Measurement

Ongoing
This multifaceted program leverages expertise in three complementary technical focus areas- all of which involve SI-traceable measurements of relevant atmospheric species such as carbon dioxide, methane, water vapor and oxygen. The efforts include gravimetrically based preparation of primary
BCARS image of tissue sample

Broadband Coherent Anti-Stokes Raman Scattering (BCARS) Microscopy

Ongoing
Impact There is a need for label-free chemical microscopy in medicine, biology and materials science. Most of the current methods use chemical labels that often disturb the distribution and nature of chemical components being investigated. The method we are developing enables noninvasive and rapid
Measurement Assurance Framework

Building Measurement Confidence for Cell Characterization

Ongoing
NIST collaborates with key stakeholders in industry, other government agencies, and academia to develop measurement assurance strategies and advanced measurement capabilities for cell characterization. Data and concepts developed through workshops and laboratory programs inform the development of