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Material Measurement Laboratory

Projects/Programs

Displaying 51 - 75 of 566
BCARS image of tissue sample

Broadband Coherent Anti-Stokes Raman Scattering (BCARS) Microscopy

Ongoing
Impact There is a need for label-free chemical microscopy in medicine, biology and materials science. Most of the current methods use chemical labels that often disturb the distribution and nature of chemical components being investigated. The method we are developing enables noninvasive and rapid
Measurement Assurance Framework

Building Measurement Confidence for Cell Characterization

Ongoing
NIST collaborates with key stakeholders in industry, other government agencies, and academia to develop measurement assurance strategies and advanced measurement capabilities for cell characterization. Data and concepts developed through workshops and laboratory programs inform the development of

Cancer Biomarker Measurements and Collaborations

Ongoing
Collaborations and Cooperative Research Agreements We welcome collaborations and can help with assay validation and development of reference materials. Below are some examples of our collaborations and ways we can develop test materials. Early Detection Research Network (EDRN): Interagency agreement
GIAB Logo

Cancer Genome in a Bottle

Ongoing
Goals: This project is an extension of the Genome in a Bottle Consortium to develop the technical infrastructure (reference standards, reference methods, and reference data) to enable translation of cancer genome sequencing to clinical practice and innovations in technologies. The priority of GIAB

Carbon Capture, Use, and Storage

Ongoing
Carbon Capture, Use, and Storage (CCUS) requires a suite of technologies to capture carbon dioxide from industrial point sources, the atmosphere, and the ocean; convert carbon dioxide into products such as fuels, chemical feedstocks, and building materials; and sequester carbon dioxide deep
Image showing a variety of gas tanks with carbon dioxide

Carbon Dioxide Measurements and Reference Materials

Ongoing
CO 2 Reference Materials The Gas Sensing Metrology Group at NIST has a long history of providing reference materials to industry, monitoring communities, and academia. The program began in the 1970’s by developing an initial suite of CO2 primary standard mixtures (PSMs) to support the US Department
Carbon capture as CO2 reducing with emission utilization tiny person concept. Greenhouse gas pollution control with sequestration process vector illustration.

Carbon Dioxide Removal Consortium

Ongoing
Industry is developing a variety of carbon capture and removal techniques including nature-based, hybrid, and engineered solutions. The scientific understanding, measurements, and models of these complex systems are still evolving. Furthermore, advanced technologies that enhance the applicability
PHOTOsrm2483andSEM

Carbon Nanotube Reference Materials

Completed
Carbon nanomaterials are expected to play an important role in future technological developments of transistors, photovoltaics, transparent thin film conductors, sensors, and fuel cell electrodes among many potential applications. However, the potential of these materials has been hindered by a lack
medical devices Intro_fig

Cardiac Device Reliability

Ongoing
Impact and Customers This project will reduce the need for surgeries to replace failed implants, thereby improving safety and quality of life for implant recipients and reducing medical expense to society. It will provide assessment tools for the external electronic devices that support the
Wordcloud consisting of words CCQM metrology group task etc.

CCQM Activities in the Gas Analysis Working Group

Ongoing
The results from these Key comparisons will be used to benchmark the appropriate Calibration and Measurement Claims (CMCs) of the participating NMIs. CMCs are basically the declared capabilities that an NMI offers to customers, and they are included in a searchable database at the BIPM web site
CCQM Intercomparisons

CCQM Activities in the Organic Analysis Working Group

Ongoing
The results from these studies will be used to demonstrate the capabilities of participating NMIs for their similar measurement services, and eventually benchmark the appropriate  Calibration and Measurement Capabilities (CMCs) that summarizes this capability.  NIST CMCs that directly support SI
CLIA2

Cell Line Authentication

Ongoing
Cell Line Authentication – The scientific community has responded to the misidentification of human cell lines with validated methods to authenticate these cells; however, there are few assays available for nonhuman cell line identification. We have developed multiplex polymerase chain reaction (PCR

Cell Viability for Advanced Therapies

Ongoing
In the Biosystems and Biomaterials Division at NIST, we have established several technical programs to support the development and implementation of cell viability assays in advanced therapies. These programs address key needs in cell viability assay development including selection and development

Cell-based Assay for Mechanistically-based Prediction of Cytoxicity

Completed
Ricin is a type 2 ribosome inactivating protein (RIP) belonging to the A-B family of toxins and is of particular interest because of its potential use as a biological weapon and the dearth of rapid and sensitive assays that could assist detection and decontamination. The ricin toxin inhibits protein
Photograph of three Standard Reference Materials of various soil matrices.

Certification of Three Soil SRMs for Inorganic Environmental Measurements

Completed
The three NIST soil SRMs, 2709, 2710 and 2711, have been used worldwide by hundreds of laboratories; combined sales typically exceed 800 units per year. Use of these SRMs provides our customers with tools that are essential for achieving quality assurance in the analysis of contaminant elements in

Characterization of 3D Photovoltaics

Completed
First Generation (thick layers of crystalline silicon) and Second Generation (thin films of CdTe, CIGS, and related materials) PV devices are both well established in the marketplace, with well defined techniques for fabrication and characterization. Third Generation PV encompasses a wide diversity

Charpy Machine Verification Program

Ongoing
Impact testing is required for many critical applications in the construction, machinery and equipment, defense, and energy markets. Charpy testing provides data needed to ensure the quality and reliability of structural steel products. Over 1,000 machines per year are evaluated for conformance with

Chemical/Biochemical Microsensor Science

Ongoing
Our research is focused on the basic and applied aspects of chemical sensor science and technology in the following areas: The development and evaluation of nanoscale materials, e.g., nanowires and nanotubes, for high-performance chemical sensing of gas-phase species Novel approaches for low-cost