The FEI Helios 660 dual-beam microscope combines a monochromated field emission scanning electron microscope (FE-SEM) with an advanced focused ion beam (FIB) column for fast, precise nanomachining and nanoscale structural characterization. Enhanced capabilities include simultaneous chemical characterization using energy dispersive x-ray spectroscopy and material crystallographic characterization using electron backscatter diffraction. The tool supports a variety of substrates ranging from 150 mm diameter wafers down to small pieces.