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Biochemical and Exposure Science Group

The Biochemical and Exposure Science Group at NIST Charleston provides measurement science, standards, and technology to (1) support measurements of complex biological processes through the identification and quantification of proteins, hormones and metabolites and (2) support measurements related to human and wildlife exposure to natural and man-made chemicals

About

The Biochemical and Exposure Science Group (BESG) provides the measurement science, standards, technology, and data required to support environmental and human health science. The BESG applies the analytical techniques of Nuclear Magnetic Resonance (NMR), organic mass spectrometry (MS), and optical spectroscopy for the measurement of trace organic compounds in environmental samples. These capabilities are also used for characterizing plastic pollution, profiling and measuring biomolecules (including proteins, lipids, hormones, and metabolites), and assessing environmental contaminants. The group develops reference materials, certifies standard reference materials, and disseminates reference data to improve quality assurance and harmonization of measurements, enabling the development of new technologies by NIST and its stakeholders. The BESG provides guidance, measurement services, and technology transfer to government agencies (federal, state, and local), scientific organizations, academia, and industry, and works closely with international standards organizations and National Metrology Institutes to establish comparability of measurement capabilities. The Biochemical and Exposure Science Group maintains analytical facilities at the Hollings Marine Laboratory in Charleston, South Carolina, and at the Hawaii Pacific University Center for Marine Debris Research in Waimanalo, Hawaii.

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Latest Publications

Results from a multi-laboratory ocean metaproteomic intercomparison: effects of LC-MS acquisition and data analysis procedures

Author(s)
Mak Saito, Jaclyn Saunders, Matthew McIlvin, Erin Bertrand, John Breier, Margaret Brisbin, Sophie Colston, Jaimee Compton, Tim Griffin, Judson Harvey, Robert Hettich, Pratik Jagtap, Michael Janech, Rod Johnson, Rick Keil, Hugo Kleikamp, Dasha Leary, Scott McCain, Eli Moore, Subina Mehta, Dawn Moran, Jacqui Neibauer, Benjamin Neely, Michael Jakuba, Jim Johnson, Megan Duffy, Gerhard Herndl, Richard Giannone, Ryan Mueller, Brook Nunn, Martin Pabst, Samantha Peters, Andrew Rajczewski, Elden Rowland, Brian Searle, Tim Van Den Bossche, Gary Vora, Jacob Waldbauer, Haiyan Zheng, Zihao Zhao
Metaproteomics is an increasingly popular methodology that provides information regarding the metabolic functions of specific microbial taxa and has potential

Concordant inter-laboratory derived concentrations of ceramides in human plasma reference materials via authentic standards

Author(s)
Tracey Schock, Christina Jones, Federico Torta, Nils Hoffmann, Bo Burla, Irina Alecu, Makoto Arita, Takeshi Bamba, Steffany A.L. Bennett, Justine BERTRAND-MICHEL, Britta Brugger, Mónica Molina, María Dolores Camacho Muñoz, Antonio Checa, Michael Chen, Michelle Cinel, Benoit COLSCH, Cristina Coman, Bebiana Da Costa Sousa, Alex Dickens, Maria Maria, Finnur Freyr Eiríksson, Hector Gallart-Ayala, Mohan Ghorasaini, Martin Giera, Xue Guan, Mark Haid, Thomas Hankemeier, Amy Harms, Marcus Höring, Michal Holčapek, Thorsten Hornemann, Chunxiu Hu, Andreas Hülsmeier, Julijana Ivanisevic, Harald Köfeler, Sin Man Lam, Jong Cheol Lee, Gerhard Liebisch, Andrea F Lopez-Clavijo, Malena Manzi, Peter Meikle, Maria Monge, Sneha Muralidharan, Anna Nicolaou, Valerie O'Donnell, Matej Oresic, Arvind Ramanathan, Daisuke Saigusa, Heidi Schwartz-Zimmermann, Guanghou Shui, Masatomo Takahashi, Margrét Thorsteinsdóttir, Anthony Tournadre, Hiroshi Tsugawa, Victoria Tyrrell, Grace van der Gugten, Michael Wakelam, Craig Wheelock, Denise Wolrab, Guowang Xu, John Bowden, Kim Ekroos, Robert Ahrends, Markus Wenk
In this community effort, we compared measurements between 34 laboratories from 19 countries, utilizing mixtures of authentic synthetic standards, to quantify

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Group Leader

Group Office Manager