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Bioscience

Engineering / synthetic biology

News and Updates

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Study Highlights Need for Standardized Measurement Methods in Gene Therapy

January 6, 2025

Scientists looked at multiple techniques used to measure the modified viruses deployed in some gene therapy research and treatments.

Sam Schaffter poses sitting in his office with a shoebox modified with craft supplies to be an educational model of an E. coli cell.

Social Spotlight: Engineered Cells as a Shoebox

October 19, 2024

Scientists often face a challenge in explaining their highly technical research to the general public.

Artist’s rendering of an organ-on-a-chip device

NIST-Led Working Group Developing Standards for Organ-on-a-Chip Research

February 22, 2024

When testing a new medicine, researchers must do more than assess how well that drug works. They also have to determine whether the medicine has some negative

An illustrated anatomically correct human heart sits inside of a microchip, with its valves connecting to the microchip sensors.

Heart-on-a-Chip: A Microfluidic Marvel Shaping the Future of Cardiovascular Research

February 6, 2024

Researchers at NIST have developed bioelectronic devices capable of real-time measurements of cell behavior.

A gloved hand holds a glass flask partly full of pinkish liquid, with a label in marker saying in part "NISTCHO RCB."

NIST, Partners Develop Living Reference Material for Producing Monoclonal Antibodies

January 11, 2023

Publicly available NISTCHO cell line expands the biomanufacturing and research applications of NIST’s monoclonal antibody standard, NISTmAb.

NIST Develops Yeast Material for Training First Responders on Biothreats

January 4, 2023

Researchers based the material on baker’s yeast because it is harmless and a living biological material.

Where Once Were Black Boxes, NIST’s New LANTERN Illuminates

June 22, 2022

Researchers at the National Institute of Standards and Technology (NIST) have developed a new statistical tool that they have used to predict protein function.

Revamped Design Could Take Powerful Biological Computers From the Test Tube to the Cell

March 23, 2022

Tiny biological computers made of DNA could revolutionize the way we diagnose and treat a slew of diseases, once the technology is fully fleshed out. However, a

A woman (Callie Higgins) stands in front of a piece of photopolymerization equipment.

NIST’s Callie Higgins Wins Service to America Medal

October 28, 2021

Callie I. Higgins, a materials research engineer at the National Institute of Standards and Technology (NIST), has won the Samuel J. Heyman Service to America

A multicolored sphere made up of a dense network of colored ribbons against a black background.

New Collaboration Aims to Improve Measurement of Viral Vectors Used in Cutting-Edge Gene Therapies

July 27, 2021

ROCKVILLE, Md. — The U.S. Department of Commerce’s National Institute of Standards and Technology (NIST), the National Institute for Innovation in Manufacturing

An illustration of a green sphere made of puzzle pieces against a dark background.

Scientists Develop Cell With Synthetic Genome That Grows and Divides Normally

March 29, 2021

New findings shed light on mechanisms controlling the most basic processes of life.

graphic design image of a science lab set-up with breakers and other lab equipment

Next-Generation Protein Sequencing Going Lab-to-Market

March 23, 2021

The Technology Maturation Accelerator Program (TMAP) was begun at NIST in 2019 to provide a platform for NIST scientists and engineers to help propel their lab

Spotlight: Putting NIST at the Forefront of Genome Editing

February 23, 2021

We started from the bottom and now we’re here — geneticist and molecular biologist Samantha Maragh brought NIST into a revolution for the biomedical sciences

NIST Publishes a Beginner’s Guide to DNA Origami

January 8, 2021

In a technique known as DNA origami, researchers fold long strands of DNA over and over again to construct a variety of tiny 3D structures, including miniature

A red cylinder made of lipids has five protruding multicolored proteins.

NIST Clarifies Structure of Prospective Vaccine for Respiratory Virus

December 16, 2020

No approved vaccine exists for RSV, a life-threatening virus that attacks the respiratory system. State-of-the-art neutron and X-ray scattering performed at the

A fire burns along the ground at the edge of a wooded area.

NIST Awards More Than $4 Million to Small Businesses for Innovations in AI, Wildfire Forecasting and More

October 1, 2020

GAITHERSBURG, Md. — The U.S. Department of Commerce’s National Institute of Standards and Technology (NIST) has awarded 19 small businesses in 12 states a total

A man in safety goggles gives a thumbs-up while sitting at a computer.

Spotlight: Theorizing Between Postdoc and Adviser About the Future of DNA Origami

September 22, 2020

Some assembly required — NIST postdoctoral researcher Jacob Majikes takes the smallest fragments of life and combines them into new structures ... or rather

NIST Scientists Get Soft on 3D Printing

September 22, 2020

Researchers at the National Institute of Standards and Technology (NIST) have developed a new method of 3D-printing gels and other soft materials. Published in

The Genome Editing Consortium

August 20, 2020

Genome editing is the manipulation of the genetic material of a living organism by deleting, replacing, or inserting a DNA sequence, typically with the aim of

A scientist stands in front of a book, which represents the human genome, and tries to identify the missing pieces or chapters.

NIST Develops Benchmark for Accurately Detecting Large Genetic Mutations Linked to Major Diseases

June 15, 2020

Many serious diseases, including autism, schizophrenia and numerous cardiac disorders, are believed to result from mutation of an individual’s DNA. But some

A Big Science Framework for Big Genomes

February 4, 2020

In a recent Perspectives article in Nature Communications, NIST’s Elizabeth Strychalski and co-authors from industry and academia offer a framework for

NIST Scientists and Engineers Pitch Innovations to Venture Capitalists

December 18, 2019

The Technology Partnerships Office (TPO) at the National Institute of Standards and Technology (NIST), on December 02, 2019, brought to life an event that

Tracking Lab-Grown Tissue With Light

December 12, 2019

Someday, doctors would like to grow limbs and other body tissue for soldiers who have lost arms in battle, children who need a new heart or liver, and many

Stem Cells and AI: Better Together

November 18, 2019

One day in the future when you need medical care, someone will examine you, diagnose the problem, remove some of your body’s healthy cells, and then use them to

A photo illustration of a hand holding forceps editing DNA

NIST Seeks Comments on Genome Editing Terms

September 18, 2019

The NIST Genome Editing Consortium seeks feedback on terms and definitions specific to genome editing. The purpose of this project is to encourage the use of a

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