NIST Traveling Tunable Laser Projector (TTLP) for UV-Blue Disinfection Dose Determinations

Published

June 21, 2022

Author(s)

Thomas C. Larason, Steven Grantham, Clarence Zarobila, Yuqin Zong, C Cameron Miller, Michael Schuit, Brian Holland, Stewart Wood, Melissa Krause

Abstract

As COVID-19 was overtaking the world in the spring of 2020, the National Institute of Standards and Technology began collaborating with the National Biodefense Analysis and Countermeasures Center to study the inactivation of SARS-CoV-2 to different UV and blue light wavelengths. This paper describes a 1 kHz pulsed laser and projection system used to study the doses required to inactive SARS-CoV-2 over the wavelength range of 222 nm–488 nm. This paper builds on NIST's previous work for water pathogen inactivation using UV laser irradiation. The design of the laser and projection system and its performance in the Biosafety Level 3 (BSL-3) laboratory are given. The SARS-CoV-2 inactivation results published elsewhere (Publication by Schuit, M.A., et al., expected 2022), demonstrate that a tunable laser projection system is an invaluable tool for this research.

Citation

Applied Optics

Volume

61

Issue

19

Pub Type

Journals

Download Paper

https://doi.org/10.1364/AO.460317

Local Download

Keywords

Action Spectra, SARS-CoV-2 Inactivation, Ultraviolet Light, Blue Light, Tunable Laser

Citation

Larason, T. , Grantham, S. , Zarobila, C. , Zong, Y. , Miller, C. , Schuit, M. , Holland, B. , Wood, S. and Krause, M. (2022), NIST Traveling Tunable Laser Projector (TTLP) for UV-Blue Disinfection Dose Determinations, Applied Optics, [online], https://doi.org/10.1364/AO.460317, https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=933993 (Accessed November 23, 2024)