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Search Publications by: Carl G. Simon, Jr., Ph.D. (Fed)

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Displaying 176 - 200 of 265

X-Ray Imaging Optimization of 3D Tissue Engineering Scaffolds via Combinatorial Fabrication Methods

April 1, 2008
Author(s)
Yanyin Yang, Shauna M. Dorsey, Matthew Becker, Sheng Lin-Gibson, Gary E. Schumacher, Glenn M. Flaim, J Kohn, Carl G. Simon Jr.
We have developed a combinatorial method for determining optimum tissue scaffold composition for imaging by X-ray techniques. X-ray radiography and microcomputed tomography enable non-invasive imaging of implanted materials in vivo and in vitro

Cell Adhesion and Spreading on Poly(D,L-lactic acid) Films Pre-Aged in Cell Medium

January 1, 2008
Author(s)
Ruby I. Chen, Nathan D. Gallant, Jack R. Smith, Matt J. Kipper, Carl G. Simon Jr.
From a biomaterials perspective, three primary events can occur when a biodegradable polymer is implanted in vivo: 1) polymer degradation, 2) protein adsorption to the polymer and 3) swelling of the polymer as it absorbs water. These actions can affect the

Combinatorial Polymer Scaffold Libraries

November 1, 2007
Author(s)
Carl G. Simon Jr., J S. Stephens, Matthew Becker
We have developed a method for fabricating combinatorial libraries of porous, three-dimensional, salt-leached, polymer scaffolds that can be used for screening the effect of scaffold properties on cell response. Syringe pumps, tubing and a static mixer are

Combinatorial Method for Determining Optimum Tissue Scaffold Composition for Imaging by X-Ray Techniques

April 12, 2006
Author(s)
Carl G. Simon Jr., Yanyin Yang, Shauna M. Dorsey, Gary E. Schumacher, Glenn M. Flaim, J Kohn, Sheng Lin-Gibson, Matthew Becker
X-ray imaging techniques can be very useful for tissue engineering applications. The ability to image radiopaque medical implants in vivo with X-ray radiography enables clinicians to conveniently, inexpensively and non-invasively monitor wound healing and

In Vitro Cytotoxicity of Amorphous Calcium Phosphate Composites

May 1, 2005
Author(s)
Carl Simon Jr., Joseph M. Antonucci, D W. Liu, Drago Skrtic
Calcium phosphate-based biomaterials are being widely used as bone substitutes in dentistry as well as reconstructive and orthopedic surgery because of their generally accepted good biocompatibility, osteoconductivity and/or bone-bonding properties. Among