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Search Publications by: Carl G. Simon, Jr., Ph.D. (Fed)

Displaying 201 - 225 of 265

Blends From In Situ Photopolymerization of Poly(ethylene Glycol) Dimethacrylate Polylactide Mixtures (Poster)

April 1, 2005

Author(s)

K J. Zhang, Carl Simon Jr., Joseph M. Antonucci, Sheng Lin-Gibson

Miscible or partially miscible blends of crosslinked-PEGDMA and PLA were prepared using a unique combination of mixing and photo-polymerization processes. Through careful selection of components and the control of processing conditions, the properties of

Fast Setting Calcium Phosphate-Chitosan Scaffold: Mechanical Properties and Biocompatibility

April 1, 2005

Author(s)

H H. Xu, Carl Simon Jr.

Cytotoxicity of three-dimensionally ordered macroporous solugel bioactive glass (3DOM-BG)

January 1, 2005

Author(s)

K Zhang, N. R. Washburn, Carl G. Simon Jr.

High-Throughput Screening of Cell Proliferation on Poly(L-lactic acid)/Poly(D,L-lactic acid) Blends

January 1, 2005

Author(s)

Carl Simon Jr., Naomi Eidelman, Scott B. Kennedy, Amit Sehgal, C A. Khatri, N. R. Washburn

)We have combined automated fluorescence microscopy with a combinatorial approach for creating polymer blend gradients to yield a high-throughput method for characterizing cell proliferation on polymer blends. A gradient in polymer blend composition of

In Situ Formation of Blends By Photopolymerization of Poly(ethylene glycol) Dimethacrylate and Polylactide

January 1, 2005

Author(s)

K J. Zhang, Carl Simon Jr., N Washburn, Joseph M. Antonucci, Sheng Lin-Gibson

Blends of crosslinked poly(ethylene glycol dimethacrylate) (PEGDMA) with poly (D, L-lactide) (PLA) were prepared by mixing photo-activated PEGDMA (molecular mass: 875 g/mol) and PLA, and subsequently photopolymerizing with visible light. The effects of PLA

Premixed Rapid-Setting Calcium Phosphate Composites for Bone Repair

January 1, 2005

Author(s)

Lisa E. Carey, Hockin D. Xu, Carl Simon Jr., Shozo Takagi, Laurence C. Chow

Abstract (A-2000 character or less factual summary of most significant information. If document includes a significant bibliography or literature survey, cite it here. Spell out acronyms on first reference.) Although calcium phosphate cement (CPC) is

Strong, Macroporous and in-Situ Hardening Hydroxyapatite Scaffold for Bone Tissue Engineering

January 1, 2005

Author(s)

H H. Xu, Carl Simon Jr., S. Takagi, Laurence Chow, F Eichmiller

Effect of Nanoscale Surface Roughness of Polymeric Biomaterials on Cell Function (Poster session)

December 25, 2004

Author(s)

Carl G. Simon Jr., Naomi Eidelman, N Washburn

Surface roughness can affect cell adhesion, morphology, proliferation and differentiation. Since polymeric biomaterials can inherently exhibit nanometer-scale surface roughness, we have investigated the influence of polymeric nanotopology on cell function

High-Throughput Method for Determining Modulus of Polymer Blends

December 1, 2004

Author(s)

Carl G. Simon Jr., Naomi Eidelman, Y N. Deng, N Washburn

Polymer blending is commonly used to create materials with improved mechanical properties, but the resulting material properties can have a complex dependence on composition and processing conditions (Paul, 1986). In order to accelerate polymer-blend

Combinatorial Methods for Rapid Screening of Biomaterials

October 1, 2004

Author(s)

Carl G. Simon Jr., N Washburn, S B. Kennedy, Naomi Eidelman, Y N. Deng, Eric J. Amis

Current methods for biomaterials development involve one-specimen-at-a-time characterization which is costly and time-consuming. Combinatorial and high-throughput methods hold the potential to enhance research and development in any field of scientific

Biocompatible Polymer Blends Derived From the Photopolymerization of Polyethylene Glycol Dimethacrylate-Polylactide Mixtures

August 1, 2004

Author(s)

K Zhang, Sheng Lin-Gibson, Carl G. Simon Jr., Joseph M. Antonucci, N Washburn

Miscible liquid blends of photoactivated PEGDMA and low molecular mass PLA were prepared by simple heating. Subsequent photo-polymerization of the activated PEGDMA and PLA yielded clear polymeric blends. The addition of low molecular mass PLA did not

Strong and Bioactive Composites Containing Nano-Silica-Fused Whiskers for Bone Repair

August 1, 2004

Author(s)

H H. Xu, Douglas T. Smith, Carl Simon Jr.

Self-hardening calcium phosphate cement (CPC) sets to form hydroxyapatite with high osteoconductivity, but its brittleness and low strength prohibit use in stress-bearing locations. Bioactive composites containing hydroxyapatite fillers in polymer matrices

Quantification of Inflammatory Cellular Responses Using Real-Time Polymerase Chain Reaction

May 1, 2004

Author(s)

L A. Bailey, N. R. Washburn, Carl G. Simon Jr., E S. Chan, Francis W. Wang

: The introduction of tissue engineering approaches for the repair and replacement of human body components extends the application and importance of synthetic materials (biomaterials). Implanted biomaterials frequently evoke inflammatory responses, and