Bioimaging

Orthogonal Measurements

Ongoing

Definitions: Orthogonal measurements: Measurements that use different physical principles to measure the same property of the same sample with the goal of minimizing method-specific biases and interferences. Complementary measurements: Measurements that corroborate each other to support the same

Quantitative, Traceable Determination of Cell Viability Using Absorbance Microscopy

Ongoing

The current gold standard for cell viability measurements is the trypan blue assay. Trypan blue dye enters dead cells that have a ruptured membrane. As a result, the dead cells are stained blue. Live cells with an intact membrane, on the other hand, do not absorb the dye molecules and remain

Comparing the Biological Responses of Photoluminescent Silicon Nanoparticles with Silicon Micron-sized Particles

Completed

Intended Impact Technology is now available to produce nanoparticles of uniform size and shape which may allow their use in a wide range of applications from drug delivery to water purification. The high surface area to volume ratio of nanoparticles makes them particularly good catalysts as well as

Building Measurement Confidence for Cell Characterization

Ongoing

NIST collaborates with key stakeholders in industry, other government agencies, and academia to develop measurement assurance strategies and advanced measurement capabilities for cell characterization. Data and concepts developed through workshops and laboratory programs inform the development of

News and Updates

A hand in a purple glove turns a metal dial on a plate holding tiny vials of purple liquid.

NIST Develops New Nondestructive Method for Assessing Bioengineered Artificial Tissues

Stem Cells and AI: Better Together

Images of the same basic cell type grown on two different bioscaffolds

Bioimaging

The Research

Orthogonal Measurements

Quantitative, Traceable Determination of Cell Viability Using Absorbance Microscopy

Comparing the Biological Responses of Photoluminescent Silicon Nanoparticles with Silicon Micron-sized Particles

Building Measurement Confidence for Cell Characterization

News and Updates

NIST Develops New Nondestructive Method for Assessing Bioengineered Artificial Tissues

Stem Cells and AI: Better Together

Shape-Sifting: NIST Categorizes Bio Scaffolds by Characteristic Cell Shapes