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The accurate mass determination of DNA and other nucleic acids is of critical importance in many clinical diagnoses and in forensic and molecular biological
The Biosystems and Biomaterials Division (BBD) is developing tools to take advantage of the quantum nature of light, enabling new biological measurements as
Drug overdose deaths continue to rise in the United States. Timely data on the drug landscape is difficult to obtain due to a constantly changing drug supply
National Institute of Standards and Technology (NIST) fossil fuel Standard Reference Materials (SRMs) continue to be in high demand by the petroleum industry
Luminescence measurements have become the methods of choice for new clinical and biochemical analyses due to their high selectivity and sensitivity. At the same
Energy is one of the most critical problems facing the United States, with technical, economic, and public policy aspects. Our group develops state-of-the-art
The Centers for Disease Control and Prevention (CDC) collects data on elemental composition of human body fluids and tissues as part of major studies such as
In 1999, the U.S. Fish and Wildlife Service Alaska Maritime National Wildlife Refuge (USFWS-AMNWR), the U.S. Geological Survey Biological Resources Division
The use of cluster sources such as C 60 and argon gas cluster ion beams (Ar GCIB) allow for the analysis of the subsurface volume. It can also minimize the
Significant environmental remediation efforts are being conducted to address the hazards posed by the long-term terrestrial disposal of hexavalent chromium in
For decades, NIST has provided the SRM 3100 series single-element standard solutions. The certified values are traceable to the International System of Units
Sensitive and fully state resolved spectroscopic methods in the terahertz (THz) and ultraviolet (UV) regions are being developed to investigate the structure
Microbeam X-ray fluorescence (µXRF) has been used nondestructively to investigate elemental heterogeneity by constructing two-dimensional maps of elemental
After enactment of the CPSIA, a collaboration was established between the Consumer Product Safety Commission (CPSC) and NIST for the purpose of developing tools
The Chemical Sciences Division is involved in development of standards and reference materials for restricted hazardous substances through participation in
Surface desorption ambient mass spectrometry enables direct solid surface interrogation for sampling and ionization of trace analytes. This project encompasses
The National Institute of Standards and Technology is responsible for providing an evaluated tandem mass spectral library for reliable compound identification
Mass spectrometry is an important technique in analytical chemistry, essential in areas including drug development, criminal and agricultural forensics
Thermal desorption ambient mass spectrometry decouples analyte desorption and ionization. Here, analytes are thermally desorbed directly from a primary surface
Time-of-flight secondary ion mass spectrometry (ToF-SIMS) employs a pulsed primary ion beam and a time-of-flight mass analyzer for the detection of molecular
Standard Reference Materials® ( SRMs®) and commercially produced, NIST-traceable materials for UV/visible/NIR spectrophotometry are transfer standards that
The Gas Sensing Metrology Group in the Chemical Sciences Division is tasked with providing traceability in gas analysis for the U.S. This group works with
The following videos and corresponding narrated PowerPoint presentations are provided for training and education in chemical metrology. Each presentation
Gadolinium-Based Contrast Agents (GBCA) are intravenous drugs used in diagnostic imaging procedures to enhance the quality of magnetic resonance imaging (MRI)
Protein drugs are the fastest-growing class of drugs in the pharmaceutical industry. However, they can be plagued by long-term stability issues, including