Projects/Programs

Displaying 1 - 6 of 6

Assay Development for Cell-Free Expression Systems

Ongoing

Current practices for characterizing cell-free expression systems are limited and unsuitable to advance these technologies beyond the state-of-the-art. To meet this measurement need, the Cellular Engineering Group is developing quantitative assays to benchmark cell extracts, reagents, and cell-free

Gears illustrating NIST's cell-free systems initiatives

Metrology For Cell-Free Expression Systems

Ongoing

Cell-free expression systems are poised to advance the US bioeconomy and play a key role in ensuring US manufacturing resilience. NIST has several, on-going projects in its growing portfolio to promote reproducibility, new measurement methods, and best practices and standards in cell-free expression

NIST Living Measurement Systems Foundry

Ongoing

To enable the production of high-throughput, high-quality data that meets the rapidly evolving needs of current and future stakeholders, NIST has established an automation facility for the growth, manipulation, sample preparation, and measurement of engineered microbes. The core of the facility

Test tube illustrating NIST cell-free workshop topics

NIST Workshops on Cell-Free Expression Systems

Completed

NIST has co-hosted two cell-free workshops. NIST CELL-FREE (Comparable Engineered Living Lysates For Research Education and Entrepreneurship) Workshop (2019) The NIST CELL-FREE workshop took place in La Jolla, CA in February 2019, in collaboration with the J. Craig Venter Institute (JCVI). The

Protocols, datasets, and software for engineering biology

Ongoing

Published protocols, datasets, and software for engineering biology from the Cellular Engineering Group. Protocols Romantseva E., Ross D., Alperovich N., Strychalski E., Automated DNA template preparation and quantitation methods, https://www.protocols.io, March 23, 2022, https://dx.doi.org/10.17504

RNA Computation and Metrology for Engineering Biology

Ongoing

RNA computation RNA computation, i.e., programmed interactions between RNA molecules that process information, is an increasingly useful synthetic biology tool with applications spanning in vitro biosensing, synthetic cells, and cellular control. We have developed cotranscriptionally encoded RNA

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---Quantum Measurement Division
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Cell-free systems

Projects/Programs