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Bioscience

Transcriptomics

The Research

PFAS to RNA-seq to RNA circuits

Engineering Living Measurement Systems to Sense PFAS

Ongoing
Per- and polyfluoroalkyl substances, PFAS, are thermodynamically stable organic fluorinated chemicals that are resistant to traditional degradation pathways leading to concern for bioaccumulation. These compounds originate from several industrial manufacturing processes and are found in soil systems
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Cancer Genome in a Bottle

Ongoing
Goals: This project is an extension of the Genome in a Bottle Consortium to develop the technical infrastructure (reference standards, reference methods, and reference data) to enable translation of cancer genome sequencing to clinical practice and innovations in technologies. The priority of GIAB

Measuring Antimicrobial Resistance

Ongoing
Antibiotic resistance has been identified in the Nation’s Action Plan to improve the health and wellbeing of the American people. NIST scientists are leveraging a wide range of measurement capabilities to study microbial community dynamics with regard to antimicrobial resistance. Using a range of
ctRSD toolkit overview

RNA Computation and Metrology for Engineering Biology

Ongoing
RNA computation RNA computation, i.e., programmed interactions between RNA molecules that process information, is an increasingly useful synthetic biology tool with applications spanning in vitro biosensing, synthetic cells, and cellular control. We have developed cotranscriptionally encoded RNA

News and Updates

A flowchart depicts the steps in which an RNA component of a biological circuit is produced.

Revamped Design Could Take Powerful Biological Computers From the Test Tube to the Cell

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