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The NIST Rapid Microbial Testing Methods (RMTM) Consortium addresses the need for measurements and standards, including reference materials, to increase
The NIST Urine Albumin Standardization Program is focused on the development of a measurement procedure and reference materials to support an international
The latest release of the NIST Mass Spectral Library, which includes the NIST Tandem Mass Spectral Library and NIST/EPA/NIH Mass Spectral Library and NIST GC
Many computer-based inferences in contemporary biology are comparative and would benefit from the rigorous and flexible approach of evolutionary comparative
The sizing and counting of subvisible particles in the size range 2 μm to 100 μm is an essential component of product quality assurance in therapeutic protein
This NIST-wide collaborative project aims to improve biotechnology and medical diagnostics by increasing the resolution and precision of measurements of cells
Reliable measurements of quality attributes of medical products are required for quality control and verification of safety and efficacy. To reduce (i) the risk
NIST and FDA are co-developing DNA-based materials for mixed microbial detection. Our annual workshop brings together private and public interests to discuss
The National Institute of Standards and Technology is developing a peptide mass spectral library as an extension of the NIST/EPA/NIH Mass Spectral Library
We have made available a method to characterize a fluorescence microscope's performance by benchmarking the detection threshold, saturation and linear dynamic
The COVID-19 pandemic highlighted the need for an agile and resilient pharmaceutical manufacturing and distribution framework. Advancements in manufacturing
We engage with leaders in the pharmaceutical, dental, and personal care research sectors that rely on water soluble polymers (polyelectrolytes) to develop new
The manufacture of polymeric materials from their raw form into their final useful product occurs under highly non-equilibrium conditions where temperature and
We measured the levels of modified DNA bases following ү-irradiation of the halophilic archaeon, Halobacterium sp. str. NRC-1. In this first study to quantify
Our goal is to address critical measurement issues that exist regarding chemical and physical stability of biomacromolecules (proteins and DNA) in hydrophilic
Therapeutic protein solutions are highly concentrated during manufacturing purification processes and in finished dosage. At such concentrations, the fluid
Background: Collagen type 1 is the most prevalent extracellular protein in connective tissue, and is part of the family of collagens that are fibril forming
A major focus at NIST is to apply measurement assurance tools to improve the performance of any cell-based assay to achieve a high-end, high-quality documentary
Flow cytometers are versatile instruments that have been successfully used to enumerate cell subsets in infectious diseases (e.g., HIV) and to diagnose
Microscopy images of cells are often used in cell biology to qualitatively identify features of interest and to discern differences between treatments. Images
Flow cytometry is a widely used technique for single-cell and particle analysis. For flow cytometry to be used in a clinical, industrial, or research setting