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The Quantitative MRI project develops calibration structures (phantoms) and validates quantitative imaging protocols for magnetic resonance imaging (MRI)
The Biosystems and Biomaterials Division (BBD) is developing tools to take advantage of the quantum nature of light, enabling new biological measurements as
The certification for all SRM neutral density filters expires after two years. We maintain a program to recertify such filters produced by us. Filters returned
Luminescence measurements have become the methods of choice for new clinical and biochemical analyses due to their high selectivity and sensitivity. At the same
The Resonating Platforms project is focused on developing resonant-acoustic devices and methods for characterizing the interactions of microbes with chemical
The NIST Regenerative Medicine and Advanced Therapies (RMAT) laboratory programs are focused on developing innovative measurement assurance solutions and
RNA is an increasingly attractive molecule for engineering biology, in part due to the sequence-programmable nature of RNA:RNA interactions. The Cellular
The global response to COVID-19 is leading to rapid advances in diagnostic, surveillance, and vaccine and therapeutic development. A critical measurement
Control over engineering and measuring single cells is an emerging capability of value to increase confidence the sectors of engineering biology, regenerative
Nanopores offer the potential to study a wide range of protein-related phenomena that includes unfolding kinetics, differences in unfolding pathways, protein
SMART contrast agent project develops multifunctional imaging contrast agents including nano-fabricated agents that can sense and report local properties.
Contamination of waterways with fecal material leads to the dissemination of pathogens and antibiotic-resistant bacteria that can have serious impacts on human
Immunohistochemistry (IHC) is used to visualize antigens in tissue sections by specific antigen-antibody interactions, an advantage over traditionally used
Metagenomics, or identifying the organisms present in a sample through DNA-based analysis, is a revolutionary technology made possible through advances in
Obtaining high confidence field detection, identification, and quantification of microbial samples remains a challenge. Since 9/11 and the subsequent anthrax
First responders continually receive calls regarding suspicious materials that are potentially biological threat materials. Obtaining high confidence data from
Sensitive and fully state resolved spectroscopic methods in the terahertz (THz) and ultraviolet (UV) regions are being developed to investigate the structure
NIST is developing Wide Scale Digital Optical Microscopy (WISDOM) as an advanced measurement capability for imaging induced pluripotent stem cells (iPSCs) and
We are resolving critical measurement issues that prevent researchers from reliably predicting the chemical and physical storage stability of biomacromolecules
We are witnessing the emergence of a web based "data rich" era on chemical and biological compounds. In order to make significant advances in this "data rich"
Developing and maintaining a nationwide capability in field biological assessment requires routine training with biological materials. Attenuated biothreat
Protein-based drugs can degrade by aggregation into micrometer-sized particles. Such particles, although only a minute fraction of the total protein, sometimes