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Automation
BBD is advancing biometrology and engineering biology by delivering state-of-the-art measurement capabilities through the integration of its expertise in metrology with automation, ML/AI, and experimental design. Examples of specific automation facilities and automated workflows in BBD include the Living Measurement Systems Foundry (LMSF) and the Prototype Cell Assay Measurement Platform (PCAMP).
To support the dissemination of best practices and the broader adoption of automation for biometrology and engineering biology, BBD participates in the Global Biofoundry Alliance and engages in active outreach with industry, academic, and government stakeholders.
CURRENT ACTIVIties and products
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Living Measurement Systems Foundry (LMSF) – enables high-throughput, in vivo characterization of the function of engineered proteins and their effects on cell fitness. |
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Prototype Cell Assay Measurement Platform (PCAMP) – enables the execution of large design-of-experiment (DoE) layouts to directly identify and evaluate the sources of variability in bioassays and facilitate the generation of high-quality assay protocols for research and industrial applications. |
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Nucleic Acid Library Preparation – enables the preparation of libraries of DNA and RNA for sequencing and other applications, in a manner compatible with subsequent high-throughput, automated measurements. |
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Automated Workflows for Expression Cell-free Systems – are enabled by the capabilities of the LMSF, as well as an acoustic liquid handler, small volume positive displacement liquid handler, and larger volume eVolver system, to meet the goals of our programs in cell-free expression systems and cell computation. |